GNF-5

  • Chemical Properties
CAS No. 778277-15-9 Cat. No. BCP08970
Name GNF-5
Synonyms GNF 5; GNF5;
Formula C20H17F3N4O3 M. Wt 418.37
  • Biological Activity
Description GNF-5, an analogue of GNF-2 with improved pharmacokinetic properties, is a selective non-ATP competitive inhibitor of Bcr-Abl with an IC50 value of 0.22±0.1 uM (Wild type Abl).
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets Src/Bcr Abl 

Structure

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