NVP DPP 728 dihydrochloride

  • Chemical Properties
CAS No. 247016-69-9 Cat. No. BCP08983
Name NVP DPP 728 dihydrochloride
Synonyms NVP-728; DPP-728; NVP-DPP-728; NVP-728; DPP-728; NVP-DPP-728; DPP-728 HCl; DPP-728 dihydrochloride;NVP DPP 728;
Formula C15H18N6O.2HCl M. Wt 371.27
  • Biological Activity
Description NVP DPP 728 dihydrochloride is a DPP-IV (CD26) inhibitor. NVP DPP 728 dihydrochloride displays >15,000 fold selectivity over DPP-II and a range of Pro-cleaving proteases. The compound is shown to improve Glc tolerance, increase GLP-1 and Insuling levels, augments insulin secretion and GLUT-2 levels, and preserves islet size.
Pathways Protease/Metabolic Enzyme 
Targets DPP 

Structure

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