Photochlor
| CAS No. | 149402-51-7 | Cat. No. | BCP08986 |
| Name | Photochlor | ||
| Synonyms | HPPH; | ||
| Formula | C39H48N4O4 | M. Wt | 636.82 |
| Description | Photochlor (HTTP) is a lipophilic, second-generation, chlorin-based photosensitizer. Upon intravenous administration, HPPH selectively accumulates in the cytoplasm of cancer or pre-cancerous cells. When laser light is applied, a photodynamic reaction between HPPH and oxygen occurs, resulting in the production of cytotoxic free radicals and singlet oxygen and free radical-mediated cell death. Compared to the first-generation photosensitizer porfimer sodium, HPPH shows improved pharmacokinetic properties and causes only mild skin photosensitivity which declines rapidly within a few days after administration. | ||
| Pathways | Others Pathway | ||
| Targets | Others | ||
Structure
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