PX12

  • Chemical Properties
CAS No. 141400-58-0 Cat. No. BCP08978
Name PX12
Synonyms PX 12; PX-12;IV-2;IV2;IV 2;
Formula C7H12N2S2 M. Wt 188.31
  • Biological Activity
Description PX-12 is an irreversible inhibitor of Trx-1 currently in clinical development as an antitumor agent. The research results suggest that the lowering of elevated levels of plasma Trx-1 in cancer patients may provide a surrogate for the inhibition of tumor Trx-1 by PX-12. Furthermore, PX-12 decreases plasma VEGF levels which may contribute to the antitumor activity of PX-12.
Pathways Others Pathway 
Targets Others 

Structure

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