阿莫伦特盐酸盐
| CAS号 | 913358-93-7 | 货号 | BCP08993 |
| 中文名 | 阿莫伦特盐酸盐 | ||
| 英文名 | Almorexant HCl | ||
| 中文别名 | |||
| 英文别名 | Almorexant hydrochloride;ACT-078573 hydrochloride; ACT 078573 hydrochloride; ACT078573 hydrochloride; | ||
| 分子式 | C29H31F3N2O3.HCl | 分子量 | 549.03 |
| 生物活性 | Almorexant HCl, also known as ACT-078573, is an orexin antagonist, functioning as a competitive receptor antagonist of the OX1 and OX2 orexin receptors, which was being developed by the pharmaceutical companies Actelion and GSK for the treatment of insomnia. Development of the drug was abandoned in January 2011. Almorexant is a competitive, dual OX1 and OX2 receptor antagonist and selectively inhibits the functional consequences of OX1 and OX2 receptor activation, such as intracellular Ca2+ mobilization. | ||
| 上下游产品 | 871224-64-5（阿莫伦特） | ||
| 信号通路 | GPCR/G Protein | ||
| 靶 点 | OX Receptor | ||
结构式
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