Cetirizine hydrochloride

  • Chemical Properties
CAS No. 83881-52-1 Cat. No. BCP09018
Name Cetirizine hydrochloride
Synonyms
Formula C21H26Cl2N2O3 M. Wt 425.35
  • Biological Activity
Description Cetirizine hydrochloride is a potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Cetirizine hydrochloride is a carboxylated metabolite of hydroxyzine that acts as a selective Histamine H1 receptor inverse agonist. Compared to its parent compound, it shows similar antihistaminic activity, but with greater H1 selectivity and less sedative effects.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets Histamine Receptor 

Structure

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