Cetirizine hydrochloride
CAS No. | 83881-52-1 | Cat. No. | BCP09018 |
Name | Cetirizine hydrochloride | ||
Synonyms | |||
Formula | C21H26Cl2N2O3 | M. Wt | 425.35 |
Description | Cetirizine hydrochloride is a potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Cetirizine hydrochloride is a carboxylated metabolite of hydroxyzine that acts as a selective Histamine H1 receptor inverse agonist. Compared to its parent compound, it shows similar antihistaminic activity, but with greater H1 selectivity and less sedative effects. | ||
Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
Targets | Histamine Receptor |
Structure
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