PTC-209

  • Chemical Properties
CAS No. 315704-66-6 Cat. No. BCP09028
Name PTC-209
Synonyms PTC 209;PTC209;
Formula C17H13Br2N5OS M. Wt 495.19
  • Biological Activity
Description PTC-209 inhibits both the UTR-mediated reporter expression and endogenous BMI-1 expression in human colorectal HCT116 and human fibrosarcoma HT1080 tumor cells. PTC-209 decreases colorectal tumor cell growth in a BMI-1-dependent way. In addition, PTC-209 impairs colorectal cancer-initiating cells (CICs) through irreversible growth inhibition.
Pathways Wnt/Stem Cell 
Targets BMI1 

Structure

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