PTC-209
CAS No. | 315704-66-6 | Cat. No. | BCP09028 |
Name | PTC-209 | ||
Synonyms | PTC 209;PTC209; | ||
Formula | C17H13Br2N5OS | M. Wt | 495.19 |
Description | PTC-209 inhibits both the UTR-mediated reporter expression and endogenous BMI-1 expression in human colorectal HCT116 and human fibrosarcoma HT1080 tumor cells. PTC-209 decreases colorectal tumor cell growth in a BMI-1-dependent way. In addition, PTC-209 impairs colorectal cancer-initiating cells (CICs) through irreversible growth inhibition. | ||
Pathways | Wnt/Stem Cell | ||
Targets | BMI1 |
Structure
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