Bazedoxifene
| CAS No. | 198481-32-2 | Cat. No. | BCP09094 |
| Name | Bazedoxifene | ||
| Synonyms | WAY-140424; WAY140424; WAY 140424; TSE 424; TSE424; TSE-424; | ||
| Formula | C30H34N2O3 | M. Wt | 470.6 |
| Description | Bazedoxifene is a selective estrogen receptor modulator (SERM) currently in development for osteoporosis prevention and treatment. Preclinical and clinical studies with bazedoxifene demonstrate more tissue selectivity than other SERMs. In particular, bazedoxifene has minimal if any agonist activity in the uterus and is able to antagonize effects of estrogen on the uterus. Animal studies and early clinical studies suggest effects in the bone similar to other SERMs with prevention of postmenopausal bone loss. | ||
| Pathways | Hormone Pathay | ||
| Targets | Estrogen Receptor | ||
Structure
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