Felbamate
| CAS No. | 25451-15-4 | Cat. No. | BCP27941 |
| Name | Felbamate | ||
| Synonyms | W-554; W 554; W554; ADD-03055; ADD03055; ADD 03055; | ||
| Formula | C11H14N2O4 | M. Wt | 238.24 |
| Description | Felbamate is an anti-epileptic drug used in the treatment of epilepsy. Felbamate has been proposed to a unique dual mechanism of action as a positive modulator of GABAA receptors and as a blocker of NMDA receptors, particularly isoforms containing the NR2B subunit. Although it is clear that felbamate does cause pharmacological inhibition of NMDA receptors, the relevance of NMDA receptor blockade as a strategy for the treatment of human epilepsy has been questioned. Therefore, the importance of the effects of felbamate on NMDA receptors to its therapeutic action in epilepsy is uncertain. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | AMPA/NMDA | ||
Structure
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