Clemastine fumarate

Description	Clemastine fumarate is a histamine H1 antagonist used as the hydrogen fumarate in hay fever, rhinitis, allergic skin conditions, and pruritus. Clemastine fumarate blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial and gastrointestinal smooth muscles, including vasodilation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscles. It may cause cause drowsiness. This drug also prevents histamine-induced pain and itching of mucous membranes.
Pathways	Neuro Signaling Pathway GPCR/G Protein
Targets	Histamine Receptor

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