格列吡嗪
| CAS号 | 29094-61-9 | 货号 | BCP09195 |
| 中文名 | 格列吡嗪 | ||
| 英文名 | Glipizide | ||
| 中文别名 | |||
| 英文别名 | CP 28720; K 402;CP28720; K402;CP-28720; K-402; | ||
| 分子式 | C21H27N5O4S | 分子量 | 445.54 |
| 生物活性 | Glipizide is a short-acting, second-generation, blood-glucose-lowering agent belonging to the sulfonylurea class that increases the release of endogenous insulin from β-cells by blocking potassium channels. The drug-formulated version of Glipizide, marketed as Glucotrol or under generic label, is most commonly prescribed to lower blood sugar levels in type 2 diabetes. Glipizide is rapidly absorbed, has a very quick onset of action and a short half-life. This agent is extensively metabolized in the liver and the metabolites as well as the unchanged form are excreted in the urine. | ||
| 信号通路 | Ion Channel/Membrane Transporter | ||
| 靶 点 | Potassium Channel | ||
结构式
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