SR 1001
| CAS No. | 1335106-03-0 | Cat. No. | BCP09202 |
| Name | SR 1001 | ||
| Synonyms | SR-1001;SR1001; | ||
| Formula | C15H13F6N3O4S2 | M. Wt | 477.4 |
| Description | Retinoic acid receptor-related orphan receptors (ROR) α and γ inverse agonist (Ki values are 172 and 111 nM for RORα and RORγ respectively). Demonstrates no activity at RORβ or LXR. Suppresses TH17 cell differentiation and cytokine expression and reduces the severity of disease in an animal model of mulitple sclerosis. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | ROR | ||
Structure
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