Ezetimibe Ketone

  • Chemical Properties
CAS No. 191330-56-0 Cat. No. BCP09273
Name Ezetimibe Ketone
Synonyms Ezetimibe Intermediate-X;EZM-K;
Formula C24H19F2NO3 M. Wt 407.41
  • Biological Activity
Description Ezetimibe Ketone is Phase-I metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes.
Pathways NFκB 
Targets Keap1 Nrf2 

Structure

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