Sertaconazole nitrate

  • Chemical Properties
CAS No. 99592-39-9 Cat. No. BCP09311
Name Sertaconazole nitrate
Synonyms FI 7056;FI-7056;FI7056;
Formula C20H15Cl3N2OS.HNO3 M. Wt 500.78
  • Biological Activity
Description Sertaconazole Nitrate is the nitrate salt form of sertaconazole, a synthetic imidazole derivative with antifungal property. Sertaconazole nitrate inhibits fungal cytochrome P-450 sterol C-14 alpha-demethylation, resulting in the accumulation of fungal 14 alpha-methyl sterols and the inhibition of ergosterol synthesis, an essential component of the cell membrane of fungi. This leads to a disruption of cell membrane permeability and leakage of adenine triphosphate (ATP) and other constituents from fugal cells.
Pathways Microbiology/Virology 
Targets Antifungal 

Structure

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