Prucalopride Succinate

  • Chemical Properties
CAS No. 179474-85-2 Cat. No. BCP09320
Name Prucalopride Succinate
Synonyms R-108512; R 108512; R108512;
Formula C18H26ClN3O3.C4H6O4 M. Wt 485.96
  • Biological Activity
Description Prucalopride succinate is a selective, high affinity 5-HT4 receptor agonist with pKi of 8.6/8.1 for 5-HT4a/4b.Prucalopride, also known as R-108512, is a selective, high affinity serotonin (5-HT4) receptor agonist with enterokinetic activities. Prucalopride alters colonic motility patterns via serotonin 5-HT4 receptor stimulation: it stimulates colonic mass movements, which provide the main propulsive force for defecation. Prucalopride was approved for use in Europe in 2009.
Related Products 179474-81-8(Prucalopride hydrochloride) 179474-81-8(Prucalopride)
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets 5 HT Receptor/Serotonin Receptor 

Structure

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