Alexidine

  • Chemical Properties
CAS No. 22573-93-9 Cat. No. BCP09349
Name Alexidine
Synonyms 1,1′-hexamethylene-bis[5-(2-ethylhexyl)biguanide];
Formula C26H56N10 M. Wt 508.798
  • Biological Activity
Description Alexidine is an amphipathic bisbiguanide with a structure consisting of two (2-ethylhexyl)guanide units linked by a hexamethylene bridge. It has a role as an antibacterial agent.Alexidine is a selective inhibitor of protein tyrosine phosphatases localized to mitochondrion 1 (PTPMT1) (IC50 = 1.08 μM in vitro). Stimulates increased insulin secretion by β-cells in rat pancreatic islets. Displays antitcancer properties in FaDu cells.
Pathways Microbiology/Virology 
Targets Antibiotic 

Structure

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