Alexidine
CAS No. | 22573-93-9 | Cat. No. | BCP09349 |
Name | Alexidine | ||
Synonyms | 1,1′-hexamethylene-bis[5-(2-ethylhexyl)biguanide]; | ||
Formula | C26H56N10 | M. Wt | 508.798 |
Description | Alexidine is an amphipathic bisbiguanide with a structure consisting of two (2-ethylhexyl)guanide units linked by a hexamethylene bridge. It has a role as an antibacterial agent.Alexidine is a selective inhibitor of protein tyrosine phosphatases localized to mitochondrion 1 (PTPMT1) (IC50 = 1.08 μM in vitro). Stimulates increased insulin secretion by β-cells in rat pancreatic islets. Displays antitcancer properties in FaDu cells. | ||
Pathways | Microbiology/Virology | ||
Targets | Antibiotic |
Structure
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