N6022

  • Chemical Properties
CAS No. 1208315-24-5 Cat. No. BCP09367
Name N6022
Synonyms N-6022;N 6022;
Formula C24H22N4O3 M. Wt 414.46
  • Biological Activity
Description N6022 is a potent, selective, reversible, and efficacious S-nitrosoglutathione reductase (GSNOR) inhibitor and is currently undergoing clinical development for the treatment of acute asthma. GSNOR is a member of the alcohol dehydrogenase family (ADH) and regulates the levels of S-nitrosothiols (SNOs) through catabolism of S-nitrosoglutathione (GSNO).
Pathways Protease/Metabolic Enzyme 

Structure

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