Nicergoline

  • Chemical Properties
CAS No. 27848-84-6 Cat. No. BCP09390
Name Nicergoline
Synonyms Nicotergoline; Nimergoline; Sermion;
Formula C24H26BrN3O3 M. Wt 484.39
  • Biological Activity
Description Nicergoline is an ergot derivative used to treat senile dementia and other disorders with vascular origins. It has been found to increase mental agility and enhance clarity and perception. It decreases vascular resistance and increases arterial blood flow in the brain, improving the utilization of oxygen and glucose by brain cells. It has similar vasoactive properties in other areas of the body, particularly the lungs. Nicergoline is used for vascular disorders such as cerebral thrombosis and atherosclerosis, arterial blockages in the limbs, Raynaud's disease, vascular migraines, and retinopathy.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets Adrenergic Receptor 

Structure

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