OSI420 HCl
| CAS No. | 183320-51-6 | Cat. No. | BCP28007 |
| Name | OSI420 HCl | ||
| Synonyms | OSI-420; OSI 420; CP473420; CP-473420; CP 473420; OSI420 HCL;Desmethyl erlotinib;O-Desmethylerlotinib hydrochloride; | ||
| Formula | C21H21N3O4.HCl | M. Wt | 415.88 |
| Description | OSI-420 is an active metabolite of erlotinib, which is a potent EGFR tyrosin kinase inhibitor. OSI-420 (CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway | ||
| Targets | EGFR | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.