钙蛋白酶抑制剂I
CAS号 | 110044-82-1 | 货号 | BCP28014 |
中文名 | 钙蛋白酶抑制剂I | ||
英文名 | MG101 | ||
中文别名 | ALLN 钙蛋白酶抑制剂; | ||
英文别名 | Calpain Inhibitor I; MG-101; MG 101; ALLN; AcLLnLCHO; Ac-LLnL-CHO;Ac-Leu-Leu-Nle-Aldehyde;Acetylleucyl-leucyl-norleucinal; | ||
分子式 | C20H37N3O4 | 分子量 | 383.53 |
生物活性 | MG-101 is a calpain inhibitor (IC50 = 0.09 μM) that activates p53-dependent apoptosis in tumor cell lines. Activities of MG-101 includes: (1) reduce colon injury caused by dinitrobenzene sulphonic acid; (2) overcome acquired resistance to TRAIL; (3) protect against atractyloside-induced toxicity. (4). reduce colon injury caused by dinitrobenzene sulphonic acid. | ||
信号通路 | Protease/Metabolic Enzyme | ||
靶 点 | Proteasome |
结构式
![](https://img.biochemsafebuy.com/uploads/company8/20191009/1570605613_hxlmf.gif)
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