Cabozantinib L-Malate Salt

  • Chemical Properties
CAS No. 1140909-48-3 Cat. No. BCP09448
Name Cabozantinib L-Malate Salt
Synonyms Cabozantinib (S)-Malate(XL-184);
Formula C28H24FN3O5.C4H6O5 M. Wt 635.59
  • Biological Activity
Description A orally available and potent inhibitor of multiple receptor tyrosine kinases (RTK), specifically MET and VEGFR2. It also inhibits KIT, FLT3, Tie-2, RET and AXL.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets TAM Receptor c Met VEGFR c Kit Tie2 FLT3 

Structure

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