MK8742

  • Chemical Properties
CAS No. 1444832-51-2 Cat. No. BCP09464
Name MK8742
Synonyms Elbasvir;MK-8742;MK 8742;Elbasvir intermediate;Elbasvir-D6;
Formula C49H55N9O7 M. Wt 882.04
  • Biological Activity
Description Elbasvir, also known as MK-8742, is a HCV NS5A inhibitor, which is currently in phase 2b clinical trials as part of an all-oral, interferon-free regimen for the treatment of HCV infection. The NS5A protein plays a critical role in the replication of HCV and has been the focus of numerous research efforts over the past few years. NS5A inhibitors have shown impressive in vitro potency profiles in HCV replicon assays, making them attractive components for inclusion in all oral combination regimens.
Pathways Protease/Metabolic Enzyme Microbiology/Virology 
Targets HCV Protease HCV 

Structure

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