MK8742
| CAS号 | 1444832-51-2 | 货号 | BCP09464 |
| 中文名 | MK8742 | ||
| 英文名 | MK8742 | ||
| 中文别名 | |||
| 英文别名 | Elbasvir;MK-8742;MK 8742;Elbasvir intermediate;Elbasvir-D6; | ||
| 分子式 | C49H55N9O7 | 分子量 | 882.04 |
| 生物活性 | Elbasvir, also known as MK-8742, is a HCV NS5A inhibitor, which is currently in phase 2b clinical trials as part of an all-oral, interferon-free regimen for the treatment of HCV infection. The NS5A protein plays a critical role in the replication of HCV and has been the focus of numerous research efforts over the past few years. NS5A inhibitors have shown impressive in vitro potency profiles in HCV replicon assays, making them attractive components for inclusion in all oral combination regimens. | ||
| 信号通路 | Protease/Metabolic Enzyme Microbiology/Virology | ||
| 靶 点 | HCV Protease HCV | ||
结构式
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