SKLB1002
| CAS No. | 1225451-84-2 | Cat. No. | BCP09480 |
| Name | SKLB1002 | ||
| Synonyms | SKLB-1002;SKLB 1002; | ||
| Formula | C13H12N4O2S2 | M. Wt | 320.39 |
| Description | SKLB1002 shows strikingly lower cytotoxicity on normal human cells L-02. SKLB1002 significantly inhibits HUVEC proliferation, migration, invasion, and tube formation, by inhibiting VEGF-induced phosphorylation of VEGFR2 kinase and the downstream protein kinases including ERK, FAK, and Src. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | VEGFR | ||
Structure
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