BIBX 1382

  • Chemical Properties
CAS No. 196612-93-8 Cat. No. BCP09515
Name BIBX 1382
Synonyms Falnidamol;BIBX-1382;BIBX1382;
Formula C18H21Cl3FN7 M. Wt 387.84
  • Biological Activity
Description BIBX 1382 displays > 1000-fold lower potency against ErbB2 (IC50 = 3.4 μM) and a range of other related tyrosine kinases (IC50 > 10 μM). Oral administration inhibits growth of established human xenografts in athymic mice.
Pathways Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway 
Targets EGFR 

Structure

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