BIBX 1382
CAS No. | 196612-93-8 | Cat. No. | BCP09515 |
Name | BIBX 1382 | ||
Synonyms | Falnidamol;BIBX-1382;BIBX1382; | ||
Formula | C18H21Cl3FN7 | M. Wt | 387.84 |
Description | BIBX 1382 displays > 1000-fold lower potency against ErbB2 (IC50 = 3.4 μM) and a range of other related tyrosine kinases (IC50 > 10 μM). Oral administration inhibits growth of established human xenografts in athymic mice. | ||
Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway | ||
Targets | EGFR |
Structure
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