Cilastatin sodium

CAS No.	81129-83-1	Cat. No.	BCP09574
Name	Cilastatin sodium
Synonyms	Cilastatin; Cilastatine; Cilastatinum; MK 0791; MK 791; M K-791; MK0791; MK791;
Formula	C16H24N2Na2O5S	M. Wt	402.42

Description	Cilastatin is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Dehydropeptidase is an enzyme found in the kidney and is responsible for degrading the antibiotic imipenem. Cilastatin can therefore be combined intravenously with imipenem in order to protect it from dehydropeptidase and prolong its antibacterial effect. Cilastatin itself does not have antibiotic activity although it has been proved to be active against a zinc-dependent beta-lactamase that usually confer antibiotic resistance to certain bacteria.
Pathways	GPCR/G Protein
Targets	Leukotriene Receptor

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