Obeticholic acid
| CAS No. | 459789-99-2 | Cat. No. | BCP09598 |
| Name | Obeticholic acid | ||
| Synonyms | 6-Ethylchenodeoxycholic acid; INT 747; INT-747; INT747; 6-ECDCA; Ocaliva; | ||
| Formula | C27H46O4 | M. Wt | 420.63 |
| Description | Obeticholic Acid (INT747; 6-ECDCA) is a novel derivative of cholic acid which acts as a potent and selective FXR agonist displaying anticholeretic activity in an in vivo rat model of cholestasis. It inhibits vascular smooth muscle cell inflammation and migration as well as promotes adipocyte differentiation and regulates adipose cell function in vivo. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | FXR | ||
Structure
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