WHI-P154
| CAS No. | 211555-04-3 | Cat. No. | BCP09619 |
| Name | WHI-P154 | ||
| Synonyms | WHI-P154; WHI-P 154; | ||
| Formula | C16H14BrN3O3 | M. Wt | 376.2 |
| Description | WHI-P154 is a potent JAK3 inhibitor with IC50 of 1.8 μM, no activity against JAK1 or JAK2, also inhibits EGFR, Src, Abl, VEGFR and MAPK, prevents Stat3, but not Stat5 phosphorylation. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway Wnt/Stem Cell Epigenetics | ||
| Targets | EGFR JAK | ||
Structure
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