Bretazenil

  • Chemical Properties
CAS No. 84379-13-5 Cat. No. BCP09629
Name Bretazenil
Synonyms Ro 16-6028; Ro 16 6028; Ro16-6028; Ro 166028; Ro 166028; Ro166028;Brn 4765855;
Formula C19H20BrN3O3 M. Wt 418.29
  • Biological Activity
Description Bretazenil, also known as Ro 16-6028, is GABA A receptor agonist potentially for the treatment of anxiety disorders. Bretazenil differs from traditional 1,4-benzodiazepines by being a partial agonist and because it binds to α1, α2, α3, α4, α5 and α6 subunit containing GABAA receptor benzodiazepine receptor complexes. 1,4-benzodiazepines bind only to α1, α2, α3 and α5 GABAA benzodiazepine receptor complexes.
Pathways Ion Channel/Membrane Transporter Neuro Signaling Pathway 
Targets GABA Receptor 

Structure

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