PEAQX

  • Chemical Properties
CAS No. 459836-30-7 Cat. No. BCP09649
Name PEAQX
Synonyms NVP-AAM077; NVP-AAM 077; NVP-AAM-077; AAM-077; AAM077; AAM 077;
Formula C34H32Br2N6Na4O11P2 M. Wt 1014.37
  • Biological Activity
Description PEAQX, also known as NVP-AAM077; is a competitive antagonist at the NMDA receptor. Although originally described as 100-fold selective for GluN1/GluN2A receptors vs. GluN1/GluN2B receptors, more detailed studies of the Ki of PEAQX revealed it only shows a 5 fold difference in affinity for GluN1/GluN2A vs. GluN1/GluN2B receptors. It is also a potent anticonvulsant in animal tests.
Pathways Ion Channel/Membrane Transporter 
Targets AMPA/NMDA 

Structure

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