SQ 22536

  • Chemical Properties
CAS No. 17318-31-9 Cat. No. BCP28072
Name SQ 22536
Synonyms SQ22536; SQ 22536; SQ-22,536; SQ22,536; SQ 22,536;
Formula C9H11N5O M. Wt 205.22
  • Biological Activity
Description SQ-22536 is an inhibitor of adenylyl cyclase with an IC50 value of 13 μM. SQ 22536 prevents the antiplatelet effect of dazoxiben, a thromboxane-synthetase inhibitor. SQ 22536 inhibited adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] activity of crude membrane preparations from catfish (Ictalurus melas) and rat isolated hepatocytes in a non-competitive manner.
Pathways GPCR/G Protein 
Targets Adenylate Cyclase 

Structure

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