STF-118804
| CAS No. | 894187-61-2 | Cat. No. | BCP09741 |
| Name | STF-118804 | ||
| Synonyms | STF118804;STF 118804; | ||
| Formula | C25H23N3O4S | M. Wt | 461.53 |
| Description | STF-118804 reduces the viability of B-ALL cell lines containing MLL chromosomal translations, with IC50 values in the low nanomolar range. In addition, leukemic samples from ?ve pediatric ALL patients are also sensitive to STF-118804 in the low nanomolar range. STF-118804 induces leukemia MV411 cell apoptosis without antecedent cell cycle arrest. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | Nampt | ||
Structure
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