FIPI

CAS No.	939055-18-2	Cat. No.	BCP09746
Name	FIPI
Synonyms	5-Fluoro-2-Indolyl des-Chlorohalopemide;
Formula	C23H24FN5O2	M. Wt	421.47

Description	FIPI is a potent and selective phospholipase D inhibitor. FIPI attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. FIPI rapidly blocks in vivo PA production with subnanomolar potency. We were surprised to find that several biological processes blocked by 1-butanol are not affected by FIPI, suggesting the need for re-evaluation of proposed FIPI does inhibit PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis, indicating potential utility for it as a therapeutic for autoimmunity and cancer metastasis.
Pathways	Protease/Metabolic Enzyme
Targets	Phospholipase

Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.

For product details of different batches, please contact our Customer

Products are for research use only and not for human use. We do not sell to patients.