Tazobactam acid

  • Chemical Properties
CAS No. 89786-04-9 Cat. No. BCP09757
Name Tazobactam acid
Synonyms YTR830; YTR 830; YTR-830; AC7620; AC 7620; AC-7620; DB01606; DB 01606; DB-01606; CL298741; CL 298741; CL-298741; Tazobactam;
Formula C10H12N4O5S M. Wt 300.29
  • Biological Activity
Description Tazobactam inhibits the action of bacterial β-lactamases, especially those belonging to the SHV-1 and TEM groups. It is commonly used as its sodium salt, tazobactam sodium. Tazobactam is combined with the extended spectrum β-lactam antibiotic piperacillin in the drug piperacillin/tazobactam, one of the preferred antibiotic treatments for nosocomial pneumonia caused by Pseudomonas aeruginosa.[medical citation needed] Tazobactam broadens the spectrum of piperacillin by making it effective against organisms that express β-lactamase and would normally degrade piperacillin. Tazobactam is derived from the penicillin nucleus and is a penicillinic acid sulfone.
Pathways Microbiology/Virology 
Targets Antibiotic 

Structure

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