XMD17-109
| CAS No. | 1435488-37-1 | Cat. No. | BCP09844 |
| Name | XMD17-109 | ||
| Synonyms | XMD17109;XMD 17109; | ||
| Formula | C36H46N8O3 | M. Wt | 638.8 |
| Description | In vitro: The pAP1-luciferase reporter and pRL-CMV-Renilla plasmids were co-transfected with plasmids encoding for ERK5 and constitutively active MEK5 (MEK5DD) in HEK293 cells. Cells were treated with the indicated amounts of compound 26 (XMD17-109) for 24 h, and lysates were subjected to the dual-luciferase assay. Compound 26 completely inhibited the ERK5-mediated AP1 transcriptional activity at 30 μM and had an EC50 of 4.2 ± 0.7 μM. By contrast 24 had an EC50 of >30 μM. | ||
| Pathways | MAPK Pathway | ||
| Targets | MEK/ERK | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.