(E)-Triapine
| CAS No. | 236392-56-6 | Cat. No. | BCP09945 |
| Name | (E)-Triapine | ||
| Synonyms | NSC663249;NSC 663249;NSC-663249;AIDS-179996;AIDS179996;AIDS 179996;[(E)-(3-aminopyridin-2-yl)methylideneamino]thiourea; | ||
| Formula | C7H9N5S | M. Wt | 195.24 |
| Description | Triapine inhibits the enzyme ribonucleotide reductase, resulting in the inhibition of the conversion of ribonucleoside diphosphates to deoxyribonucleotides necessary for DNA synthesis. This agent has been shown to inhibit tumor growth in vitro. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | DNA/RNA Synthesis | ||
Structure
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