CC-223
| CAS No. | 1228013-30-6 | Cat. No. | BCP09953 |
| Name | CC-223 | ||
| Synonyms | CC 223;CC223;Onatasertib; | ||
| Formula | C21H27N5O3 | M. Wt | 397.47 |
| Description | Onatasertib, also known as CC-223, is an orally available inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. mTOR kinase inhibitor CC-223 inhibits the activity of mTOR, which may result in the induction of tumor cell apoptosis and a decrease in tumor cell proliferation. mTOR, a serine/threonine kinase that is upregulated in a variety of tumors, plays an important role downstream in the PI3K/AKT/mTOR signaling pathway, which is frequently dysregulated in human cancers. | ||
| Pathways | PI3K/Akt/mTOR | ||
| Targets | mTOR | ||
Structure
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