(-)-Blebbistatin
CAS No. | 856925-71-8 | Cat. No. | BCP09979 |
Name | (-)-Blebbistatin | ||
Synonyms | (S)-(-)-Blebbistatin; | ||
Formula | C18H16N2O2 | M. Wt | 292.336 |
Description | (-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM in cell-free assays, does not inhibit myosin light chain kinase, inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. | ||
Pathways | Ion Channel/Membrane Transporter | ||
Targets | ATPase |
Structure
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