FLLL32
| CAS号 | 1226895-15-3 | 货号 | BCP28141 |
| 中文名 | FLLL32 | ||
| 英文名 | FLLL32 | ||
| 中文别名 | |||
| 英文别名 | FLLL-32; FLLL 32; | ||
| 分子式 | C28H32O6 | 分子量 | 464.55 |
| 生物活性 | FLLL32, a novel curcumin analogue, is a potent STAT3 inhibitor. FLLL32 specifically reduced STAT3 phosphorylation at Tyr705 (pSTAT3) and induced apoptosis at micromolar amounts in human melanoma cell lines and primary melanoma cultures. FLLL32 promoted loss of cell proliferation at lower concentrations than curcumin leading to caspase-3- dependent apoptosis. FLLL32 may have potential for targeting multiple myeloma, glioblastoma, liver cancer, and colorectal cancer cells expressing constitutive STAT3 signaling. | ||
| 信号通路 | Jak/Stat Pathway Wnt/Stem Cell | ||
| 靶 点 | Stat | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！