Brexpiprazole

  • Chemical Properties
CAS No. 913611-97-9 Cat. No. BCP10218
Name Brexpiprazole
Synonyms OPC 34712;OPC34712;OPC 34712;
Formula C25H27N3O2S M. Wt 433.57
  • Biological Activity
Description IC50 Value: N/A Target: Dopamine Receptor in vitro: Brexpiprazole (OPC-34712) is a close structural analog of aripiprazole and shares some of its pharmacological properties. Similarly to aripiprazole, brexpiprazole exhibits partial agonism of D2R and an enhanced affinity for specific serotonin receptors (e.g., 5-HT1A, 5-HT2A and 5-HT7). Currently. in vivo: Brexpiprazole is in Phase III clinical trials for patients with schizophrenia and as adjunctive therapy for patients with major depressive disorder .
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets 5 HT Receptor/Serotonin Receptor Dopamine Receptor 

Structure

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