Brexpiprazole
CAS No. | 913611-97-9 | Cat. No. | BCP10218 |
Name | Brexpiprazole | ||
Synonyms | OPC 34712;OPC34712;OPC 34712; | ||
Formula | C25H27N3O2S | M. Wt | 433.57 |
Description | IC50 Value: N/A Target: Dopamine Receptor in vitro: Brexpiprazole (OPC-34712) is a close structural analog of aripiprazole and shares some of its pharmacological properties. Similarly to aripiprazole, brexpiprazole exhibits partial agonism of D2R and an enhanced affinity for specific serotonin receptors (e.g., 5-HT1A, 5-HT2A and 5-HT7). Currently. in vivo: Brexpiprazole is in Phase III clinical trials for patients with schizophrenia and as adjunctive therapy for patients with major depressive disorder . | ||
Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
Targets | 5 HT Receptor/Serotonin Receptor Dopamine Receptor |
Structure
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