Magnolin
| CAS No. | 31008-18-1 | Cat. No. | BCP10271 |
| Name | Magnolin | ||
| Synonyms | Epimagnolin; | ||
| Formula | C23H28O7 | M. Wt | 416.46 |
| Description | Magnolin is a major pharmacologically active ingredient derived from Shin-i, the dried flower buds of Magnolia fargesii (Magnoliaceae) that has been used for the treatment of empyema, nasal congestion, sinusitis, and allergic rhinitis. Magnolin inhibits the Ras/ERKs/RSK2 signaling axis by targeting the active pocket of ERK1 and ERK2 with IC50s of 87 nM and 16.5 nM, respectively. | ||
| Pathways | MAPK Pathway | ||
| Targets | MEK/ERK | ||
Structure
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