Ivermectin

  • Chemical Properties
CAS No. 70288-86-7 Cat. No. BCP10431
Name Ivermectin
Synonyms MK-0933;MK 0933;MK0933;
Formula C48H74O14 M. Wt 875.09
  • Biological Activity
Description Ivermectin (22,23-dihydroavermectin B1a + 22,23-dihydroavermectin B1b) is a broad-spectrum antiparasitic avermectin medicine. Ivermectin is positive allosteric modulator of the α7 neuronal nicotinic acetylcholine receptor and the purinergic P2X4 receptor. Antihelmintic. Ivermectin also modulates glutamate- and GABA-activated chloride channels. Ivermectin potentiates glycine-gated currents at low concentrations (30 nM).
Pathways Microbiology/Virology 
Targets Antiparasitics 

Structure

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