Ivermectin
CAS No. | 70288-86-7 | Cat. No. | BCP10431 |
Name | Ivermectin | ||
Synonyms | MK-0933;MK 0933;MK0933; | ||
Formula | C48H74O14 | M. Wt | 875.09 |
Description | Ivermectin (22,23-dihydroavermectin B1a + 22,23-dihydroavermectin B1b) is a broad-spectrum antiparasitic avermectin medicine. Ivermectin is positive allosteric modulator of the α7 neuronal nicotinic acetylcholine receptor and the purinergic P2X4 receptor. Antihelmintic. Ivermectin also modulates glutamate- and GABA-activated chloride channels. Ivermectin potentiates glycine-gated currents at low concentrations (30 nM). | ||
Pathways | Microbiology/Virology | ||
Targets | Antiparasitics |
Structure
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