BRD4770
| CAS No. | 1374601-40-7 | Cat. No. | BCP10433 |
| Name | BRD4770 | ||
| Synonyms | BRD-4770;BRD 4770; | ||
| Formula | C25H23N3O3 | M. Wt | 413.47 |
| Description | BRD4770 activates the ATM pathway without inducing DNA damage, while the ATR pathway is not affected. BRD4770 is a novel probe for studying G9a and its role in cellular senescence.Treatment of 5 μM BRD4770 for 24 h decreased H3K9 trimethylation level by 23% in PANC-1 cells. BRD9539 also inhibits PRC2 activity. | ||
| Pathways | Cell Cycle/DNA Damage PI3K/Akt/mTOR Epigenetics | ||
| Targets | Histone Methyltransferase ATM/ATR | ||
Structure
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