UNC0379

  • Chemical Properties
CAS No. 1620401-82-2 Cat. No. BCP10429
Name UNC0379
Synonyms UNC 0379;UNC-0379;
Formula C23H35N5O2 M. Wt 413.56
  • Biological Activity
Description UNC0379 is a synthetic small-molecule inhibitor that displays inhibitory activity in multiple biochemical assays and is selective for SETD8 over 15 other methyltransferases. The binding a?nity of UNC0379 to SETD8 was determined using biophysical assays such as ITC (isothermal titration calorimetry) and SPR (surface plasmon resonance) and is largely consistent with its potency in biochemical assays.
Pathways Epigenetics 
Targets Histone Methyltransferase 

Structure

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