UNC0379
CAS No. | 1620401-82-2 | Cat. No. | BCP10429 |
Name | UNC0379 | ||
Synonyms | UNC 0379;UNC-0379; | ||
Formula | C23H35N5O2 | M. Wt | 413.56 |
Description | UNC0379 is a synthetic small-molecule inhibitor that displays inhibitory activity in multiple biochemical assays and is selective for SETD8 over 15 other methyltransferases. The binding a?nity of UNC0379 to SETD8 was determined using biophysical assays such as ITC (isothermal titration calorimetry) and SPR (surface plasmon resonance) and is largely consistent with its potency in biochemical assays. | ||
Pathways | Epigenetics | ||
Targets | Histone Methyltransferase |
Structure
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