SB3CT

  • Chemical Properties
CAS No. 292605-14-2 Cat. No. BCP10428
Name SB3CT
Synonyms SB-3CT;SB 3CT;
Formula C15H14O3S2 M. Wt 306.4
  • Biological Activity
Description SB-3CT is a potent matrix metalloproteinase MMP-2 and MMP-9 inhibitor. SB-3CT is a 2-[(arylsulfonyl)methyl]thiirane that achieves potent inhibition, by a thiirane-opening mechanism, of the MMP2 and MMP9 zinc metalloproteases. SB-3CT attenuates behavioral impairments and hippocampal loss after traumatic brain injury in rat. Matrix metalloproteinases (MMPs) are involved in a number of activities including angiogenesis and embryogenesis. In particular, gelatinases A (MMP-2) and B (MMP-9), are thought to facilitate tumor metastasis.
Pathways Protease/Metabolic Enzyme 
Targets MMP 

Structure

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