Idarubicin
| CAS No. | 58957-92-9 | Cat. No. | BCP10471 |
| Name | Idarubicin | ||
| Synonyms | IMI30; IMI-30; IMI 30; NSC256439; NSC-256439; NSC 256439; 4-DMDR; IDA; 4-Demethoxydaunomycin; | ||
| Formula | C26H27NO9 | M. Wt | 497.49 |
| Description | Idarubicin is a semisynthetic 4-demethoxy analogue of the antineoplastic anthracycline antibiotic daunorubicin. Idarubicin intercalates into DNA and interferes with the activity of topoisomerase II, thereby inhibiting DNA replication, RNA transcription and protein synthesis. Due to its high lipophilicity, idarubicin penetrates cell membranes more efficiently than other anthracycline antibiotic compounds. | ||
| Related Products | 57852-57-0（Idarubicin hydrochloride） | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | Topoisomerase | ||
Structure
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