Oleanolicacid

  • Chemical Properties
CAS No. 508-02-1 Cat. No. BCP10498
Name Oleanolicacid
Synonyms Oleanic acid; Caryophyllin;Astrantiagenin C;
Formula C30H48O3 M. Wt 456.71
  • Biological Activity
Description Oleanolic Acid is a GPBA receptor (TGR5) partial agonist (EC50 = 2.25 μM; 72% efficacy). It displays no activity at FXR. Also inhibits protein phosphate 1B (PTP1B) and glycogen phosphorylase. Suppresses cell proliferation and increases apoptosis in T24 bladder cancer cells. Antidiabetic, antihyperglycaemic, antitumor and hepatoprotective.
Pathways Others Pathway 
Targets Autophagy 

Structure

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