Buparlisib Hydrochloride
| CAS No. | 1312445-63-8 | Cat. No. | BCP10618 |
| Name | Buparlisib Hydrochloride | ||
| Synonyms | NVP-BKM120 HCl;BKM120 Hydrochloride; NVP-BKM120 Hydrochloride; | ||
| Formula | C18H22ClF3N6O2 | M. Wt | 446.85 |
| Description | Buparlisib Hydrochloride is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM, respectively. Reduced potency against VPS34, mTOR, DNA-PK, with little activity to PI4Kβ. | ||
| Related Products | 944396-07-0（Buparlisib ） | ||
| Pathways | PI3K/Akt/mTOR | ||
| Targets | PI3K | ||
Structure
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