KN-92 hydrochloride

  • Chemical Properties
CAS No. 1431698-47-3 Cat. No. BCP10626
Name KN-92 hydrochloride
Synonyms KN 92;KN92;
Formula C24H26Cl2N2O3S M. Wt 493.45
  • Biological Activity
Description KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). IC50 value: Target: KN-92 is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. KN-93 inhibits histamine-induced aminopyrine uptake in parietal cells (IC50 = 300 nM).
Pathways Neuro Signaling Pathway 
Targets CaMK 

Structure

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