Cefamandole formate sodium salt

CAS No.	42540-40-9	Cat. No.	BCP10739
Name	Cefamandole formate sodium salt
Synonyms	Cefamandole Nafate; Cemandil sodium salt; Cefamandol nafato; O-Formylcefamandole sodium; Cephamandole nafate;
Formula	C19H17N6NaO6S2	M. Wt	512.5

Description	Cefamandole Nafate is the sodium salt form of cefamandole formyl ester. Cefamandole nafate is a pro-drug that is hydrolyzed by plasma esterases to produce cefamandole, a semi-synthetic beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. Cefamandole binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
Pathways	Microbiology/Virology
Targets	Antibiotic

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